RRM1 is mediated by histone acetylation through gemcitabine resistance and contributes to invasiveness and ECM remodeling in pancreatic cancer

Author:

Ono Hiroaki1,Murase Yoshiki1,Yamashita Hironari1,Kato Tomotaka1,Asano Daisuke1,Ishikawa Yoshiya1,Watanabe Shuichi1,Ueda Hiroki1,Akahoshi Keiichi1,Ogawa Kosuke1,Kudo Atsushi1,Akiyama Yoshimitsu2,Tanaka Shinji2,Tanabe Minoru1

Affiliation:

1. Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo 113‑8510, Japan

2. Division of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo 113‑8510, Japan

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology

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