1. Complex Operative Unit of Medical Oncology, Uboldo Hospital, Cernusco Sul Naviglio, I‑20063 Milan, Italy
2. Department of Statistics and Quantitative Methods, University of Milan‑Bicocca, I‑20126 Milan, Italy
3. Department of Experimental and Clinical Medicine‑Medical, Veterinary and Pharmaceutical Biotechnologies, Magna Graecia University of Catanzaro, I‑88100 Catanzaro, Italy
4. Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, Istituto di Ricovero e Cura a Carattere Scientifico, I‑20141 Milan, Italy