1. Natural Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Cheongju, Chungcheongbuk‑do 28116, Republic of Korea
2. Department of Pharmacology, College of Medicine, Kangwon National University, Chuncheon 24341, Republic of Korea
3. Biotoxtech Co., Ltd., Ochang, Cheongju, Chungcheongbuk‑do 28115, Republic of Korea