Vascular endothelial growth factor B regulates insulin secretion in β cells of type 2 diabetes mellitus mice via PLCγ and the IP3R‑evoked Ca2<sup>+</sup>/CaMK2 signaling pathway-Reference-Cited by-同舟云学术

Vascular endothelial growth factor B regulates insulin secretion in β cells of type 2 diabetes mellitus mice via PLCγ and the IP3R‑evoked Ca2⁺/CaMK2 signaling pathway

Published:2023-09-05 Issue:4 Volume:28 Page:
ISSN:1791-2997
Container-title:Molecular Medicine Reports
language:
Short-container-title:Mol Med Rep

Author:

Li Yuqi¹,Li Rongrong¹,Luo Xu¹,Xu Fang¹,Yang Meizi²,Zheng Lanhui³,Wu Qihao³,Jiang Wenguo⁴,Li Yana¹

Affiliation:

1. Department of Pathophysiology, School of Basic Medicine of Binzhou Medical University, Yantai, Shandong 264000, P.R. China

2. Department of Pharmacology, School of Basic Medicine of Binzhou Medical University, Yantai, Shandong 264000, P.R. China

3. The First School of Clinical Medicine, Binzhou Medical University, Yantai, Shandong 264000, P.R. China

4. Department of Pharmacy, Binzhou Medical University, Yantai, Shandong 264000, P.R. China

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

Reference59 articles.

1. Regulation of insulin secretion in human pancreatic islets;Rorsman;Annu Rev Physiol,2013

2. Diabetes and beta cell function: From mechanisms to evaluation and clinical implications;Cernea;Biochem Med (Zagreb),2013

3. Plasma vascular endothelial growth factor B levels are increased in patients with newly diagnosed type 2 diabetes mellitus and associated with the first phase of glucose-stimulated insulin secretion function of β-cell;Wu;J Endocrinol Invest,2017

4. VEGF-B ablation in pancreatic beta-cells upregulates insulin expression without affecting glucose homeostasis or islet lipid uptake;Ning;Sci Rep,2020

5. Cardiac-specific VEGFB overexpression reduces lipoprotein lipase activity 2 and improves insulin action in rat heart;Shang;Am J Physiol Endocrinol Metab,2021

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