Discovery of microglia gonadotropin‑releasing hormone receptor and its potential role in polycystic ovarian syndrome

Author:

Wang Fan1,Zhang Zhenghong2,Han Junyong3,Zheng Jianjun4,Wang Xin1,Wang Zhengchao1

Affiliation:

1. Provincial University Key Laboratory of Sport and Health Science, School of Physical Education and Sport Sciences, Fujian Normal University, Fuzhou, Fujian 350007, P.R. China

2. Provincial Key Laboratory for Developmental Biology and Neurosciences, College of Life Sciences, Fujian Normal University, Fuzhou, Fujian 350007, P.R. China

3. Fujian Key Laboratory of Medical Measurement, Fujian Academy of Medical Sciences, Fuzhou, Fujian 350001, P.R. China

4. Department of Obstetrics and Gynecology, Fujian Provincial Hospital, Shengli Clinical College of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

Reference26 articles.

1. Activation of NLRP3 inflammasome in the ovaries during the development and treatment of polycystic ovary syndrome;Wang;Int J Clin Exp Patho,2017

2. Subacute cadmium exposure disrupts the hypothalamic-pituitary-gonadal axis, leading to polycystic ovarian syndrome and premature ovarian failure features in female rats;da Costa;Environ Pollut,2021

3. Roles of hypothalamic-pituitary-adrenal axis and hypothalamus-pituitary-ovary axis in the abnormal endocrine functions in patients with polycystic ovary syndrome;Wang;Zhongguo Yi Xue Ke Xue Yuan Xue Bao,2017

4. Hypothalamic inflammation as a potential pathophysiologic basis for the heterogeneity of clinical, hormonal, and metabolic presentation in PCOS;Barlampa;Nutrients,2021

5. Central leptin resistance and hypothalamic inflammation are involved in letrozole-induced polycystic ovary syndrome rats;Lian;Biochem Biophys Res Commun,2016

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