Iodine‑131 metabolic radiotherapy leads to cell death and genomic alterations through NIS overexpression on cholangiocarcinoma

Author:

Brito Ana1,Abrantes Ana1,Teixo Ricardo1,Pires Ana1,Ribeiro Ana1,Ferreira Rafael2,Fernandes Alexandra3,Puga Tiago1,Laranjo Mafalda1,Caramelo Francisco1,Boin Ilka4,Jefferson Douglas5,Gon�alves Ana6,Martins Ricardo7,Rodrigues Joana8,Ribeiro Ilda6,Barbosa De Melo Joana6,Sarmento-Ribeiro Ana6,Carreira Isabel6,Souza Doroteia9,Tralh�o Jos� Guilherme7,Botelho Maria1

Affiliation:

1. Biophysics Institute, Center for Neuroscience and Cell Biology and Institute for Biomedical Imaging and Life Sciences (CNC.IBILI), Faculty of Medicine, University of Coimbra, 3000‑354 Coimbra, Portugal

2. Faculty of Medical Sciences of University of Campinas (FCM/UNICAMP), Campinas, SP 13083‑887, Brazil

3. Department of Gastroenterology, Hospital de Santo Andr�, 2410-197 Leiria, Portugal

4. Laboratory of Biostatistics and Medical Informatics, Faculty of Medicine, University of Coimbra, 3000‑354 Coimbra, Portugal

5. Department of Surgery, Faculty of Medical Sciences of University of Campinas (FCM/UNICAMP), Campinas, SP 13083‑887, Brazil

6. Institute for Clinical and Biomedical Research Area of Environment Genetics and Oncobiology, Faculty of Medicine, University of Coimbra, 3000‑354 Coimbra, Portugal

7. Laboratory of Oncobiology and Hematology, Applied Molecular Biology and University Clinic of Hematology, Faculty of Medicine, University of Coimbra, 3000‑354 Coimbra, Portugal

8. Surgery Department A, Coimbra Hospital and University Centre, 3004‑531 Coimbra, Portugal

9. Department of Molecular Biology, Faculty of Medicine of S�o Jos� do Rio Preto (FAMERP), S�o Jos� do Rio Preto, SP 15090‑000, Brazil

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology

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