1. Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Kashiwa, Chiba�277‑8577, Japan
2. Department of Pathology, Exploratory Oncology Research and Clinical Trial Center, Kashiwa, Chiba�277‑8577, Japan
3. Department of Translational Oncology, National Cancer Center Research Institute, Tokyo 104‑0045, Japan
4. Department of Gastroenterology and Endoscopy, National Cancer Center Hospital East, Kashiwa, Chiba 277‑8577, Japan
5. Department of Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Chiba 277‑8577, Japan
6. Department of Esophageal Surgery, National Cancer Center Hospital East, Kashiwa, Chiba 277‑8577, Japan
7. Department of Clinical Trial Promotion, Chiba Cancer Center, Chiba 260‑8717, Japan
8. Department of Therapeutic Oncology, Kyoto University Graduate School of Medicine, Kyoto 606‑8507, Japan