Assessment of the effects of amphiphilic poly (N‑vinylpyrrolidone) nanoparticles loaded with bortezomib on glioblastoma cell lines and zebrafish embryos

Author:

Yagolovich Anne1,Kuskov Andrey2,Kulikov Pavel2,Bagrov Dmitry1,Petrova Polina1,Kukovyakina Ekaterina2,Isakova Alina2,Khan Irina3,Pokrovsky Vadim3,Nosyrev Alexander4,Stamati Polyxeni5,Markvicheva Elena6,Gasparian Marine2,Spandidos Demetrios7,Tsatsakis Aristidis4

Affiliation:

1. Faculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russian Federation

2. D. Mendeleev University of Chemical Technology of Russia, 125047 Moscow, Russian Federation

3. N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia, 115478 Moscow, Russian Federation

4. Center of Bioanalytical Research and Molecular Design, Sechenov First Moscow State Medical University, 119991 Moscow, Russian Federation

5. Department of Neurology, University Hospital of Larissa, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41100 Larissa, Greece

6. Shemyakin‑Ovchinnikov Institute of Bioorganic Chemistry of The Russian Academy of Sciences, 117997 Moscow, Russian Federation

7. Laboratory of Clinical Virology, Faculty of Medicine, University of Crete, 71003 Heraklion, Greece

Publisher

Spandidos Publications

Reference39 articles.

1. Proteasome: An emerging target for cancer therapy;Zavrski;Anticancer Drugs,2005

2. Development of the proteasome inhibitor Velcade (Bortezomib);Adams;Cancer Invest,2004

3. Velcade (Bortezomib) receives 2 new FDA indications: For retreatment of patients with multiple myeloma and for first-line treatment of patients with mantle-cell lymphoma;Raedler;Am Health Drug Benefits,2015

4. The safety of bortezomib for the treatment of multiple myeloma;Cengiz Seval;Expert Opin Drug Saf,2018

5. Pathological mechanisms of bortezomib-induced peripheral neuropathy;Yamamoto;Int J Mol Sci,2021

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