The MyD88 inhibitor, ST2825, induces cell cycle arrest and apoptosis by suppressing the activation of the NF‑κB/AKT1/p21 pathway in pancreatic cancer

Author:

Lu Sinan1,He Tianyu2,Zhang Yuan1,Zhou Bo1,Zhang Qiyi1,Yan Sheng1

Affiliation:

1. Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China

2. Key Laboratory of Precision Diagnosis and Treatment for Hepatobiliary and Pancreatic Tumor of Zhejiang Province, Hangzhou, Zhejiang 310009, P.R. China

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology,General Medicine

Reference42 articles.

1. Pancreatitis and pancreatic cancer;Saluja;Gastroenterology,2019

2. Therapeutic developments in pancreatic cancer: Current and future perspectives;Neoptolemos;Nat Rev Gastroenterol Hepatol,2018

3. Pancreatic cancer;Mizrahi;Lancet,2020

4. Cancer statistics, 2022;Siegel;CA Cancer J Clin,2022

5. Molecular targets for the treatment of pancreatic cancer: Clinical and experimental studies;Matsuoka;World J Gastroenterol,2016

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