Polo‑like kinase 1 selective inhibitor BI2536 (dihydropteridinone) disrupts centrosome homeostasis via ATM‑ERK cascade in adrenocortical carcinoma

Author:

Lin Ruei-Ci1,Chao Yu-Ying2,Lien Wei-Chih3,Chang Huei-Cih3,Tsai Shih-Wei4,Wang Chia-Yih1

Affiliation:

1. Department of Cell Biology and Anatomy, College of Medicine, National Cheng Kung University, Tainan, Taiwan 701, R.O.C.

2. Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan 709, R.O.C.

3. Department of Physical Medicine and Rehabilitation, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan 709, R.O.C.

4. Department of Obstetrics and Gynecology, An Nan Hospital, China Medical University, Tainan, Taiwan 709, R.O.C.

Publisher

Spandidos Publications

Subject

Cancer Research,Oncology,General Medicine

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