Imatinib‑ and ponatinib‑mediated cardiotoxicity in zebrafish embryos and H9c2 cardiomyoblasts

Author:

Zakaria Zain1,Suleiman Muna2,Benslimane Fatiha3,Al‑Badr Mashael4,Sivaraman Siveen5,Korashy Hesham2,Ahmad Fareed6,Uddin Shahab6,Mraiche Fatima2,Yalcin Huseyin3

Affiliation:

1. Vice President of Health and Medical Sciences Office, QU Health, Qatar University, Doha 2713, Qatar

2. Department of Pharmaceutical Sciences, College of Pharmacy, QU Health, Qatar University, Doha 2713, Qatar

3. Biomedical Research Center, Qatar University, Doha 2713, Qatar

4. Department of Biology, College of Art and Science, Qatar University, Doha 2713, Qatar

5. Translational Research Institute, Hamad Medical Corporation, Doha 3050, Qatar

6. Translational Research Institute and Dermatology Institute, Hamad Medical Corporation, Doha 3050, Qatar

Publisher

Spandidos Publications

Reference84 articles.

1. National Center for Health Statistics: Changes in the leading cause of death: recent patterns in heart disease and cancer mortality;Heron,2016

2. The development of dasatinib as a treatment for chronic myeloid leukemia (CML): From initial studies to application in newly diagnosed patients;Hochhaus;J Cancer Res Clin Oncol,2013

3. The regulatory crosstalk between kinases and proteases in cancer;López-Otín;Nat Rev Cancer,2010

4. Receptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancers;Ségaliny;J Bone Oncol,2015

5. Receptor tyrosine kinases: Biological functions and anticancer targeted therapy;Zhang;MedComm (2020),2023

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