1. Department of Integrated Oncology (CIO), University Hospital Bonn, D‑53127 Bonn, Germany
2. Department of Biosciences, Hogeschool van Arnhem en Nijmegen University of Applied Sciences, 6525EM Nijmegen, The Netherlands
3. Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, D‑53127 Bonn, Germany
4. Department of Medicine I, University Hospital Bonn, D‑53127 Bonn, Germany