Extended Hildebrand solubility approach and Yalkowsky-Roseman model for estimating the solubility of sulfadiazine and sulfamethazine in some {ethylene glycol (1) + water (2)} mixtures at several temperatures-Reference-Cited by-同舟云学术

Extended Hildebrand solubility approach and Yalkowsky-Roseman model for estimating the solubility of sulfadiazine and sulfamethazine in some {ethylene glycol (1) + water (2)} mixtures at several temperatures

Published:2022-02-04 Issue:3 Volume:50 Page:
ISSN:1909-6356
Container-title:Revista Colombiana de Ciencias Químico-Farmacéuticas
language:
Short-container-title:Rev. Colomb. Cienc. Quím. Farm.

Author:

Vargas-Santana Martha Sofía,Cruz-González Ana María,Cerquera Nestor Enrique,Escobar Rodriguez Alana Sofia,Cardenas Rossember E.,Calderón-Losada Omar,Ortiz Claudia Patricia,Delgado Daniel Ricardo

Abstract

Aim: extended Hildebrand Solubility Approach (EHSA) and Yalkowsky Roseman (YR) were applied to evaluate the solubility of sulfadiazine, and sulfamethazine in ethylene glycol + water mixtures. Methodology: reported experimental equilibrium solubilities and some fusion properties of these drugs were used for the calculations.Results: a good predictive character of EHSA (with mean deviations lower than 3.0%) were found by using regular polynomials in order two correlating the inter-action parameter W with the Hildebrand solubility parameter of solvent mixtures without drug ; however, the results obtained from YR model show relatively high deviations greater than 50%.

Publisher

Universidad Nacional de Colombia

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

Reference50 articles.

1. M.d.M. Muñoz, D.R. Delgado, M.Á. Peña, A. Jouyban, F. Martínez, Solubility and preferential solvation of sulfadiazine, sulfamerazine and sulfamethazine in propylene glycol + water mixtures at 298.15 K, J. Mol. Liq., 204, 132-136 (2015), doi: 10.1016/j.molliq.2015.01.047.

2. B. Aday, P. Sola, F. Çolak, M. Kaya, Synthesis of novel sulfonamide analogs contai-ning sulfamerazine/sulfaguanidine and their biological activities, J. Enzym. Inhib. Med. Chem., 31, 1005-1010 (2016), doi: 10.3109/14756366.2015.1079183.

3. D.R. Delgado, F. Martínez, Preferential solvation of sulfadiazine, sulfamerazine and sulfamethazine in ethanol + water solvent mixtures according to the IKBI method, J. Mol. Liq., 193, 152-159 (2014), doi: 10.1016/j.molliq.2013.12.021.

4. Regulation on Maximum Residue Limits, Salud pública, (n.d.)., URL: https://ec.europa.eu/health/veterinary-use/maximum-residue-limits/regulations_es, accessed January 29, 2021.

5. European Commission, EEC Regulation 90/2377/EEC incorporating amending regulation 92/675/EEC, Brussels, 1997, URL: https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:31997L0078&from=LV, accessed January 29, 2021.