Management of Ipsilateral Axillary Lymphadenopathy Detected on Breast Ultrasound after COVID-19 Vaccination

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted morbidity and mortality worldwide. The rollout of vaccination programs remains the most helpful action to contain coronavirus dissemination. COVID-19 vaccines are commonly administered intramuscularly into the arm. Ipsilateral axillary lymphadenopathy has been reported as an adverse event after COVID-19 vaccination. Axillary lymphadenopathy following COVID-19 vaccination may mimic metastasis. A major concern is that this finding could lead to a misdiagnosis in patients with various types of malignancy, especially breast cancer. This article reviewed the management and reports of ipsilateral axillary lymphadenopathy caused by the COVID-19 vaccine with a focus on ultrasound.