IL-1 Receptor Antagonist Reduced Chemical-Induced Keratinocyte Apoptosis through Antagonism to IL-1α/IL-1β
Author:
Affiliation:
1. Department of Dermatology, Dongguk University Seoul, Graduate School of Medicine, Goyang 10326, Republic of Korea
2. Department of Pharmacy, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea
Funder
Ministry of Health and Welfare(Ministry of Health, Welfare and Family Affairs)
National Research Foundation of Korea(NRF)
Ministry of Science, ICT and Future Planning(MSIP)
Ministry of Food and Drug Safety(MFDS)
Publisher
The Korean Society of Applied Pharmacology
Subject
Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry
Link
http://pdf.medrang.co.kr/BT2/2018/026/BT026-04-11.pdf
Reference27 articles.
1. An Autoinflammatory Disease with Deficiency of the Interleukin-1–Receptor Antagonist
2. INTERLEUKIN-1 RECEPTOR ANTAGONIST: Role in Biology
3. Biological role of interleukin 1 receptor antagonist isoforms
4. IL-1α and IL-1ra secretion from epidermal equivalents and the prediction of the irritation potential of mild soap and surfactant-based consumer products
5. Differential release of chromatin-bound IL-1 discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation
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