Aquatide Activation of SIRT1 Reduces Cellular Senescence through a SIRT1-FOXO1-Autophagy Axis

Author:

Lim Chae Jin12,Lee Yong-Moon3,Kang Seung Goo4,Lim Hyung W.5,Shin Kyong-Oh3,Jeong Se Kyoo6,Huh Yang Hoon7,Choi Suin7,Kor Myungho2,Seo Ho Seong8,Park Byeong Deog9,Park Keedon2,Ahn Jeong Keun1,Uchida Yoshikazu10,Park Kyungho1011

Affiliation:

1. Department of Microbiology and Molecular Biology, School of Bioscience and Biotechnology, Chungnam National University, Daejeon 34134, Republic of Korea

2. Peptide R&D Center, Incospharm Corporation, Daejeon 34055, Republic of Korea

3. College of Pharmacy Chungbuk National University, Cheongju 28644, Republic of Korea

4. Division of Biomedical Convergence and Institute of Bioscience & Biotechnology, Kangwon National University, Chuncheon 24341, Republic of Korea

5. Gladstone Institute of Virology and Immunology, Gladstone Institute of Neurological Disease, School of Medicine, Department of Neurology, University of California, San Francisco, CA 94158, USA

6. Department of Cosmetic Science, Seowon University, Cheongju 28674, Republic of Korea

7. Korea Basic Science Institute, Cheongju 28119, Republic of Korea

8. Radiation Biotechnology Research Division, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup 26212, Republic of Korea

9. NeoPharm USA, Englewood Cliffs, NJ 07632, USA

10. Department of Dermatology, School of Medicine, University of California, San Francisco, and Northern California Institute for Research and Education, Veterans Affairs Medical Center, San Francisco, CA

11. Department of Food Science and Nutrition, and Convergence Program of Material Science for Medicine and Pharmaceutics, Hallym University, Chuncheon 24252, Republic of Korea

Funder

Hallym University(Hallym)

Ministry of Trade, Industry and Energy(Ministry of Trade, Industry and Energy, Korea)

Korea Institute for Advancement of Technology(KIAT)

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

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