Cyclooxygenase-2 Inhibitor Parecoxib Was Disclosed as a PPAR-γ Agonist by In Silico and In Vitro Assay-Reference-Cited by-同舟云学术

Cyclooxygenase-2 Inhibitor Parecoxib Was Disclosed as a PPAR-γ Agonist by In Silico and In Vitro Assay

Published:2021-09-01 Issue:5 Volume:29 Page:519-526
ISSN:1976-9148
Container-title:Biomolecules & Therapeutics
language:en
Short-container-title:Biomolecules & Therapeutics

Author:

Xiao Bin¹,Li Dan-dan²,Wang Ying²,Kim Eun La²,Zhao Na¹,Jin Shang-Wu³,Bai Dong-Hao³,Sun Li-Dong³,Jung Jee H.²

Affiliation:

1. Laboratory of Clinical Pharmacy, Ordos Central Hospital, Ordos School of Clinical Medicine, Inner Mongolia Medical University, Ordos 017000, China

2. College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea

3. The Fourth People’s Hospital of Ordos, Ordos 017000, China

Funder

Pusan National University

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

Link

https://pdf.medrang.co.kr/BT2/2021/029/BT2029-05-519.pdf

Reference41 articles.

1. Bagi, Z., Erdei, N., Papp, Z., Edes, I. and Koller, A. (2006) Up-regulation of vascular cyclooxygenase-2 in diabetes mellitus. Pharmacol. Rep. 58, 52-56.

2. The Mechanisms of Action of PPARs

3. The Protein Data Bank

4. Role of Parecoxib Sodium in the Multimodal Analgesia after Total Knee Arthroplasty: A Randomized Double-blinded Controlled Trial

5. Adipogenesis and fat-cell function in obesity and diabetes

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