Systematic Target Screening Revealed That Tif302 Could Be an Off-Target of the Antifungal Terbinafine in Fission Yeast-Reference-Cited by-同舟云学术

Systematic Target Screening Revealed That Tif302 Could Be an Off-Target of the Antifungal Terbinafine in Fission Yeast

Published:2021-03-01 Issue:2 Volume:29 Page:234-247
ISSN:1976-9148
Container-title:Biomolecules & Therapeutics
language:en
Short-container-title:Biomolecules & Therapeutics

Author:

Lee Sol¹,Nam Miyoung¹,Lee Ah-Reum¹,Lee Jaewoong¹,Woo Jihye¹,Kang Nam Sook¹,Balupuri Anand¹,Lee Minho²,Kim Seon-Young³,Ro Hyunju⁴,Choi Youn-Woong⁵,Kim Dong-Uk⁶,Hoe Kwang-Lae¹

Affiliation:

1. Department of New Drug Development, Chungnam National University, Daejeon 34134, Republic of Korea

2. Department of Life Science, Dongguk University-Seoul, Goyang 10326, Republic of Korea

3. Personalized Genomic Research Center, Korea Research Institute of Bioscience & Biotechnology (KRIBB), Daejeon 34141, Republic of Korea

4. Department of Biological Science, College of Bioscience & Biotechnology, Chungnam National University, Daejeon 34134, Republic of Korea

5. Korea United Pharm. Inc., Seoul 06116, Republic of Korea

6. Rare Disease Research Center, Korea Research Institute of Bioscience & Biotechnology (KRIBB), Daejeon 34141, Republic of Korea

Funder

Ministry of Science and ICT, South Korea

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pdf.medrang.co.kr/BT2/2021/029/BT029-02-14.pdf

Reference64 articles.

1. Overexpression or Deletion of Ergosterol Biosynthesis Genes Alters Doubling Time, Response to Stress Agents, and Drug Susceptibility in Saccharomyces cerevisiae

2. In Vitro Activity of Terbinafine Combined with Caspofungin and Azoles against Pythium insidiosum

3. Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies

4. ELP2is a novel gene implicated in neurodevelopmental disabilities

5. Systematic exploration of synergistic drug pairs

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