Thymoquinone Suppresses Migration of Human Renal Carcinoma Caki-1 Cells through Inhibition of the PGE2-Mediated Activation of the EP2 Receptor Pathway-Reference-Cited by-同舟云学术

Thymoquinone Suppresses Migration of Human Renal Carcinoma Caki-1 Cells through Inhibition of the PGE2-Mediated Activation of the EP2 Receptor Pathway

Published:2021-01-01 Issue:1 Volume:29 Page:64-72
ISSN:1976-9148
Container-title:Biomolecules & Therapeutics
language:en
Short-container-title:Biomolecules & Therapeutics

Author:

Park Geumi¹,Song Na-Young²,Kim Do-Hee³,Lee Su-Jun⁴,Chun Kyung-Soo¹

Affiliation:

1. College of Pharmacy, Keimyung University, Daegu 42601, Republic of Korea

2. College of Dentistry, Younsei University, Seoul 03722, Republic of Korea

3. Department of Chemistry, College of Convergence and Integrated Science, Kyonggi University, Suwon 16227, Republic of Korea

4. Department of Pharmacology and Pharmacogenomics Research Center, Inje University College of Medicine, Busan 47392, Republic of Korea

Funder

Keimyung University

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pdf.medrang.co.kr/BT2/2021/029/BT029-01-08.pdf

Reference39 articles.

1. Thymoquinone inhibits the migration of mouse neuroblastoma (Neuro-2a) cells by down-regulating MMP-2 and MMP-9

2. Host knockout of E-prostanoid 2 receptors reduces tumor growth and causes major alterations of gene expression in prostaglandin E2-producing tumors

3. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

4. Distribution of metastatic sites in renal cell carcinoma: a population-based analysis

5. Salidroside reduces renal cell carcinoma proliferation by inhibiting JAK2/STAT3 signaling

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