Identification of Small GTPases That Phosphorylate IRF3 through TBK1 Activation Using an Active Mutant Library Screen-Reference-Cited by-同舟云学术

Identification of Small GTPases That Phosphorylate IRF3 through TBK1 Activation Using an Active Mutant Library Screen

Published:2023-01-01 Issue:1 Volume:31 Page:48-58
ISSN:1976-9148
Container-title:Biomolecules & Therapeutics
language:en
Short-container-title:Biomol Ther (Seoul)

Author:

Yu Jae-Hyun¹²,Moon Eun-Yi³,Kim Jiyoon¹,Koo Ja Hyun²

Affiliation:

1. Department of Pharmacology and Department of Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea

2. College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul 08826, Korea

3. Department of Bioscience and Biotechnology, Sejong University, Seoul 05006, Republic of Korea

Funder

National Research Foundation of Korea

Ministry of Science ICT and Future Planning

Seoul National University

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pdf.medrang.co.kr/BT2/2023/031/BT031-01-48.pdf

Reference45 articles.

1. Toll-like receptor 2–mediated NF-κB activation requires a Rac1-dependent pathway

2. Small GTP-binding proteins in vesicular transport

3. The small GTPase RAB1B promotes antiviral innate immunity by interacting with TNF receptor–associated factor 3 (TRAF3)

5. A role for ADP-ribosylation factor in nuclear vesicle dynamics

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