6-Shogaol and 10-Shogaol Synergize Curcumin in Ameliorating Proinflammatory Mediators via the Modulation of TLR4/TRAF6/MAPK and NFκB Translocation-Reference-Cited by-同舟云学术

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6-Shogaol and 10-Shogaol Synergize Curcumin in Ameliorating Proinflammatory Mediators via the Modulation of TLR4/TRAF6/MAPK and NFκB Translocation

Published:2022-11-02 Issue:1 Volume:31 Page:27-39
ISSN:1976-9148
Container-title:Biomolecules & Therapeutics
language:en
Short-container-title:Biomol Ther (Seoul)

Author:

Zhou Xian¹,Al-Khazaleh Ahmad¹,Afzal Sualiha²,Kao Ming-Hui (Tim)²,Münch Gerald²,Wohlmuth Hans¹³⁴,Leach David³,Low Mitchell¹,Li Chun Guang¹

Affiliation:

1. NICM Health Research Institute, Western Sydney University, Westmead, NSW 2145, Australia

2. School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia

3. Integria Healthcare, Building 5, Freeway Office Park, QLD 4113, Australia

4. School of Chemistry & Molecular Biosciences, The University of Queensland, St Lucia, QLD 4072, Australia

Funder

Australian Research Council

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pdf.medrang.co.kr/BT2/2023/031/BT031-01-27.pdf

Reference52 articles.

1. Nrf2 signaling pathway: Pivotal roles in inflammation

2. Bioavailability of Curcumin: Problems and Promises

3. Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes

4. Nrf2 Knockout Attenuates the Anti-Inflammatory Effects of Phenethyl Isothiocyanate and Curcumin

5. 6-shogaol, a active constiuents of ginger prevents UVB radiation mediated inflammation and oxidative stress through modulating NrF2 signaling in human epidermal keratinocytes (HaCaT cells)

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