Macakurzin C Derivatives as a Novel Pharmacophore for Pan-Peroxisome Proliferator-Activated Receptor Modulator-Reference-Cited by-同舟云学术

Macakurzin C Derivatives as a Novel Pharmacophore for Pan-Peroxisome Proliferator-Activated Receptor Modulator

Published:2022-11-16 Issue:3 Volume:31 Page:312-318
ISSN:1976-9148
Container-title:Biomolecules & Therapeutics
language:en
Short-container-title:Biomol Ther (Seoul)

Author:

Ko Hyejin¹,An Seungchan¹,Jang Hongjun²,Ahn Sungjin¹,Park In Guk¹,Hwang Seok Young¹,Gong Junpyo¹,Oh Soyeon¹,Kwak Soo Yeon²,Choi Won Jun³,Kim Hyoungsu²,Noh Minsoo¹

Affiliation:

1. College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 08826, Republic of Korea

2. Research Institute of Pharmaceutical Science and Technology, College of Pharmacy, Ajou University, Suwon 16499, Republic of Korea

3. College of Pharmacy, Dongguk University-Seoul, Goyang 10326, Republic of Korea

Funder

National Research Foundation of Korea

Ministry of Science and ICT, South Korea

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pdf.medrang.co.kr/BT2/2023/031/BT031-03-312.pdf

Reference26 articles.

1. A newly synthesized macakurzin C-derivative attenuates acute and chronic skin inflammation: The Nrf2/heme oxygenase signaling as a potential target

2. Discovery and Structure–Activity Relationships of Novel Template, Truncated 1′-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators

3. Selenium bioisosteric replacement of adenosine derivatives promoting adiponectin secretion increases the binding affinity to peroxisome proliferator-activated receptor δ

4. Obesity and cancer risk: Emerging biological mechanisms and perspectives

5. Synthesis and Biological Evaluation of Acetylcholinesterase Inhibitor Macakurzin C and Its Derivatives