5-Hydroxytryptophan Reduces Levodopa-Induced Dyskinesia via Regulating AKT/mTOR/S6K and CREB/ΔFosB Signals in a Mouse Model of Parkinson’s Disease-Reference-Cited by-同舟云学术

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5-Hydroxytryptophan Reduces Levodopa-Induced Dyskinesia via Regulating AKT/mTOR/S6K and CREB/ΔFosB Signals in a Mouse Model of Parkinson’s Disease

Published:2023-03-15 Issue:4 Volume:31 Page:402-410
ISSN:1976-9148
Container-title:Biomolecules & Therapeutics
language:en
Short-container-title:Biomol Ther (Seoul)

Author:

Choi Yujin¹,Huh Eugene²,Lee Seungmin¹,Kim Jin Hee¹,Park Myoung Gyu³,Seo Seung-Yong⁴,Kim Sun Yeou⁴,Oh Myung Sook¹²

Affiliation:

1. Department of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea

2. Department of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 02447, Republic of Korea

3. MetaCen therapeutics Inc. R&D Center, Suwon 16229, Republic of Korea

4. College of Pharmacy, Gachon University, Incheon 21936, Republic of Korea

Publisher

The Korean Society of Applied Pharmacology

Subject

Drug Discovery,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pdf.medrang.co.kr/BT2/2023/031/BT031-04-402.pdf

Reference50 articles.

1. Transcription Factors in Long-Term Memory and Synaptic Plasticity

2. The 5-HT1A receptor: Signaling, desensitization, and gene transcription

3. Removal of S6K1 and S6K2 leads to divergent alterations in learning, memory, and synaptic plasticity

4. Increased D1dopamine receptor signaling in levodopa-induced dyskinesia

5. Buspirone anti-dyskinetic effect is correlated with temporal normalization of dysregulated striatal DRD1 signalling in l-DOPA-treated rats

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1. Molecular Variability in Levodopa Absorption and Clinical Implications for the Management of Parkinson’s Disease;Journal of Parkinson's Disease;2024-08-31

2. Serotonergic Regulation of Synaptic Dopamine Levels Mitigates L-DOPA-Induced Dyskinesia in a Mouse Model of Parkinson’s Disease;Journal of Parkinson's Disease;2024-07-23

3. Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse;Chinese Medicine;2024-07-04

4. Gut Microbiota Metabolite Messengers in Brain Function and Pathology at a View of Cell Type-Based Receptor and Enzyme Reaction;Biomolecules & Therapeutics;2024-06-20

5. Stable indoleamines attenuate stress—A novel paradigm in tryptophan metabolism in plants;Journal of Pineal Research;2024-01-31

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