Prevention of NSAID-Induced Small Intestinal Mucosal Injury: Prophylactic Potential of Lansoprazole

Author:

Higuchi Kazuhide1,Yoda Yukiko1,Amagase Kikuko2,Kato Shinichi2,Tokioka Satoshi1,Murano Mitsuyuki1,Takeuchi Koji2,Umegaki Eiji1

Affiliation:

1. 2nd Department of Internal Medicine, Osaka Medical College

2. Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University

Publisher

The Society for Free Radical Research Japan

Subject

Clinical Biochemistry,Nutrition and Dietetics,Medicine (miscellaneous)

Reference51 articles.

1. [1] Higuchi, K., Umegaki, E., Watanabe, T., Yoda, Y., Morita, E., Murano, M., Tokioka, S., and Arakawa, T.: Present status and strategy of NSAIDs-induced small bowel injury. J. Gastroenterol., Jul 1 2009 [Epub ahead of print].

2. [2] Graham, D.Y., Opekun, A.R., Willingham, F.F., and Qureshi, W.A.: Visible small-intestinal mucosal injury in chronic NSAID users. Clin. Gastroenterol. Hepatol., 3, 55–59, 2005.

3. [3] Kameda, N., Higuchi, K., Shiba, M., Machida, H., Okazaki, H., Yamagami, H., Tanigawa, T., Watanabe, K., Watanabe, T., Tominaga, K., Fujiwara, Y., Oshitani, N., and Arakawa, T.: A prospective, single-blind trial comparing wireless capsule endoscopy and double-balloon enteroscopy in patients with obscure gastrointestinal bleeding. J. Gastroenterol., 43, 434–440, 2008.

4. [4] Watanabe, T., Sugimori, S., Kameda, N., Machida, H., Okazaki, H., Tanigawa, T., Watanabe, K., Tominaga, K., Fujiwara, Y., Oshitani, N., Higuchi, K., and Arakawa, T.: Small bowel injury by low-dose enteric-coated aspirin and treatment with misoprostol: a pilot study. Clin. Gastroenterol. Hepatol., 6, 1279–1282, 2008.

5. [5] Sugimori, S., Watanabe, T., Tabuchi, M., Kameda, N., Machida, H., Okazaki, H., Tanigawa, T., Yamagami, H., Shiba, M., Watanabe, K., Tominaga, K., Fujiwara, Y., Oshitani, N., Koike, T., Higuchi, K., and Arakawa, T.: Evaluation of small bowel injury in patients with rheumatoid arthritis by capsule endoscopy: effects of anti-rheumatoid arthritis drugs. Digestion, 78, 208–213, 2008.

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