1. The Labatt Family Heart Center, Division of Cardiology and Cardiovascular Surgery, Hospital for Sick Children and University of Toronto, Toronto, Canada
2. Department of Anesthesia and Pain Medicine, Hospital for Sick Children, Toronto, Canada
3. The Keenan Research Center for Biomedical Research of St. Michael’s Hospital, Toronto, Canada; and
4. Institute of Physiology, Charité–Universitätsmedizin Berlin, Berlin, Germany