PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2-Adrenergic Receptors and Adenylyl Cyclase 6-Reference-Cited by-同舟云学术

PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2-Adrenergic Receptors and Adenylyl Cyclase 6

Published:2018-04 Issue:4 Volume:58 Page:530-541
ISSN:1044-1549
Container-title:American Journal of Respiratory Cell and Molecular Biology
language:en
Short-container-title:Am J Respir Cell Mol Biol

Author:

Johnstone Timothy B.¹,Smith Kaitlyn H.²,Koziol-White Cynthia J.³,Li Fengying²,Kazarian Austin G.¹,Corpuz Maia L.¹,Shumyatcher Maya⁴,Ehlert Frederick J.⁵,Himes Blanca E.⁴,Panettieri Reynold A.³,Ostrom Rennolds S.¹

Affiliation:

1. Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, California

2. Department of Pharmacology, University of Tennessee Health Science Center, Memphis, Tennessee

3. Rutgers Institute for Translational Medicine and Science, Child Health Institute, Rutgers University, New Brunswick, New Jersey

4. Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania; and

5. Department of Pharmacology, School of Medicine, University of California, Irvine, Irvine, California

Publisher

American Thoracic Society

Subject

Cell Biology,Clinical Biochemistry,Pulmonary and Respiratory Medicine,Molecular Biology

Link

http://www.atsjournals.org/doi/pdf/10.1165/rcmb.2017-0294OC

Reference53 articles.

1. β-Agonist-mediated Relaxation of Airway Smooth Muscle Is Protein Kinase A-dependent

2. Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases

3. Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown

4. Choreographing the adenylyl cyclase signalosome: sorting out the partners and the steps

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