PD 102807 Induces M3 mAChR-Dependent GRK-/Arrestin-Biased Signaling in Airway Smooth Muscle Cells-Reference-Cited by-同舟云学术

PD 102807 Induces M3 mAChR-Dependent GRK-/Arrestin-Biased Signaling in Airway Smooth Muscle Cells

Published:2022-11 Issue:5 Volume:67 Page:550-561
ISSN:1044-1549
Container-title:American Journal of Respiratory Cell and Molecular Biology
language:en
Short-container-title:Am J Respir Cell Mol Biol

Author:

Tompkins Eric¹,Mimic Bogdana¹,Cuevas-Mora Karina¹,Schorsch Hannah¹,Shah Sushrut D.¹,Deshpande Deepak A.¹,Benovic Jeffrey L.²,Penn Raymond B.¹,Pera Tonio¹

Affiliation:

1. Department of Medicine, Center for Translational Medicine, Jane and Leonard Korman Respiratory Institute, Philadelphia, Pennsylvania; and

2. Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, Pennsylvania

Funder

National Institutes of Health awards

Publisher

American Thoracic Society

Subject

Cell Biology,Clinical Biochemistry,Pulmonary and Respiratory Medicine,Molecular Biology

Link

https://www.atsjournals.org/doi/pdf/10.1165/rcmb.2021-0320OC

Reference70 articles.

1. βArrestins

2. β-Arrestin-biased Agonism at the β2-Adrenergic Receptor

3. Distinct conformational changes in -arrestin report biased agonism at seven-transmembrane receptors

4. A unique mechanism of beta-blocker action: Carvedilol stimulates beta-arrestin signaling

5. Functional desensitization of the isolated beta-adrenergic receptor by the beta-adrenergic receptor kinase: potential role of an analog of the retinal protein arrestin (48-kDa protein).

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ligand bias at the muscarinic acetylcholine receptor family: Opportunities and challenges;Neuropharmacology;2024-11

2. Progress on the development of Class A GPCR‐biased ligands;British Journal of Pharmacology;2024-09-11

3. Diacylglycerol kinase is a keystone regulator of signaling relevant to the pathophysiology of asthma;American Journal of Physiology-Lung Cellular and Molecular Physiology;2024-07-01

4. Interleukin 31 receptor α promotes smooth muscle cell contraction and airway hyperresponsiveness in asthma;Nature Communications;2023-12-11

5. The biased M3 mAChR ligand PD 102807 mediates qualitatively distinct signaling to regulate airway smooth muscle phenotype;Journal of Biological Chemistry;2023-10