Lung Expression of Human Angiotensin-Converting Enzyme 2 Sensitizes the Mouse to SARS-CoV-2 Infection

Author:

Han Kun1,Blair Robert V.1,Iwanaga Naoki2,Liu Fengming13,Russell-Lodrigue Kasi E.1,Qin Zhongnan13,Midkiff Cecily C.1,Golden Nadia A.1,Doyle-Meyers Lara A.1,Kabir Mohammad E.13,Chandler Kristin E.1,Cutrera Kellie L.1,Ren Mi13,Monjure Christopher J.1,Lehmicke Gabrielle13,Fischer Tracy13,Beddingfield Brandon1ORCID,Wanek Alanna G.2,Birnbaum Angela1,Maness Nicholas J.13ORCID,Roy Chad J.13ORCID,Datta Prasun K.13,Rappaport Jay13,Kolls Jay K.2,Qin Xuebin13ORCID

Affiliation:

1. Tulane National Primate Research Center, Covington, Louisiana; and

2. Department of Medicine and Department of Pediatrics, Center for Translational Research in Infection and Inflammation, and

3. Department of Immunology and Microbiology, Tulane University School of Medicine, New Orleans, Louisiana

Publisher

American Thoracic Society

Subject

Cell Biology,Clinical Biochemistry,Pulmonary and Respiratory Medicine,Molecular Biology

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