1. Pulmonary Hypertension Research Group, Quebec Heart and Lung Institute Research Centre (IUCPQ), Québec City, Québec, Canada;
2. Department of Cardiovascular Medicine, Fukushima Medical University, Fukushima, Japan;
3. Janssen Research & Development, Spring House, Pennsylvania; and
4. Department of Medicine, Laval University, Québec City, Québec, Canada