Expression and Dynamics of Podoplanin in Cultured Osteoblasts with Mechanostress and Mineralization Stimulus

Author:

Takenawa Tomohiro1,Kanai Takenori1,Kitamura Tetsuya2,Yoshimura Yoshitaka3,Sawa Yoshihiko4,Iida Junichiro1

Affiliation:

1. Department of Orthodontics, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University

2. Department of Oral Pathology and Biology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University

3. Department of Molecular Cell Pharmacology, Faculty of Dental Medicine and Graduate School of Dental Medicine, Hokkaido University

4. Deparment of Oral Function & Anatomy, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences

Publisher

Japan Society of Histochemistry & Cytochemistry

Subject

Cell Biology,Histology,Physiology,Biochemistry,Pathology and Forensic Medicine

Reference39 articles.

1. 1 Acton, S. E., Farrugia, A. J., Astarita, J. L., Mourão-Sá, D., Jenkins, R. P., Nye, E., Hooper, S., van Blijswijk, J., Rogers, N. C., Snelgrove, K. J., Rosewell, I., Moita, L. F., Stamp, G., Turley, S. J., Sahai, E. and Reis e Sousa, C. (2014) Dendritic cells control fibroblastic reticular network tension and lymph node expansion. Nature 514; 498–502.

2. 2 Atkins, G. J., Rowe, P. S., Lim, H. P., Welldon, K. J., Ormsby, R., Wijenayaka, A. R., Zelenchuk, L., Evdokiou, A. and Findlay, D. M. (2011) Sclerostin is a locally acting regulator of late-osteoblast/preosteocyte differentiation and regulates mineral­ization through a MEPE-ASARM-dependent mechanism. J. Bone Miner. Res. 26; 1425–1436.

3. 3 Belkina, N. V., Liu, Y., Hao, J. J., Karasuyama, H. and Shaw, S. (2009) LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation. Proc. Natl. Acad. Sci. U S A 106; 4707–4712.

4. 4 Bilousova, G., Jun du, H., King, K. B., De Langhe, S., Chick, W. S., Torchia, E. C., Chow, K. S., Klemm, D. J., Roop, D. R. and Majka, S. M. (2011) Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitroand in vivo. Stem Cells 29; 206–216.

5. 5 Breiteneder-Geleff, S., Matsui, K., Soleiman, A., Meraner, P., Poczewski, H., Kalt, R., Schaffner, G. and Kerjaschki, D. (1997) Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regu-lated in puromycin nephrosis. Am. J. Pathol. 151; 1141–1152.

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