A Decrease in Glomerular Endothelial Cells and Endothelial-mesenchymal Transition during Glomerulosclerosis in the Tensin2-deficient Mice (ICGN strain)

Author:

Kato Takashi12,Mizuno Shinya13,Ito Akihiko2

Affiliation:

1. Division of Molecular Regenerative Medicine, Department of Biochemistry, Osaka University Graduate School of Medicine

2. Department of Pathology, Faculty of Medicine, Kinki University

3. Division of Virology, Department of Microbiology and Immunology, Osaka University Graduate School of Medicine

Publisher

Japan Society of Histochemistry & Cytochemistry

Subject

Cell Biology,Histology,Physiology,Biochemistry,Pathology and Forensic Medicine

Reference38 articles.

1. 1 Arciniegas, E., Frid, M. G., Douglas, I. S. and Stenmark, K. R. (2007) Perspectives on endothelial to mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension. Am. J. Physiol. Lung Cell Mol. Physiol. 293; L1–8.

2. 2 Chen, C. A., Hwang, J. C., Guh, J. Y., Tsai, J. C. and Chen, H. C. (2006) TGF-beta1 and integrin synergistically facilitate the differentiation of rat podocytes by increasing alpha-smooth muscle actin expression. Transl. Res. 148; 134–141.

3. 3 Cho, A. R., Uchio-Yamada, K., Torigai, T., Miyamoto, T., Miyoshi, I., Matsuda, J., Kurosawa, T., Kon, Y., Asano, A., Sasaki, N. and Agui, T. (2006) Deficiency of the tensin2 gene in the ICGN mouse: an animal model for congenital nephrotic syndrome. Mamm. Genome 17; 407–416.

4. 4 Fierlbeck, W., Liu, A., Coyle, R. and Ballermann, B. J. (2003) Endothelial cell apoptosis during glomerular capillary lumen formation in vivo. J. Am. Soc. Nephrol. 14; 1349–1354.

5. 5 Fogo, A. B. and Kon, V. (2010) The glomerulus—a view from the inside—the endothelial cell. Int. J. Biochem. Cell Biol. 42; 1388–1397.

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