Histomorphological changes in atheroma of the dog (morphological study on the example of 12 clinical cases)

Abstract

Pathological processes in the skin of domestic animals are one of the most common diseases of domestic animals both in the Kyrgyz Republic and throughout the world. In connection with the complex differential diagnosis of oncological and non-neoplastic diseases in animals based only on clinical signs, the purpose of this work was to conduct a statistical and histomorphological analysis of cases of atheroma development in dogs. Clinical, histological and statistical methods were used during the research. The research was conducted on a controlled group of domestic dogs in the amount of 12 animals, which were followed for several years. When collecting the anamnesis, in addition to clinical signs, the breed, age and concomitant diseases of the dogs were recorded. During surgical removal of atheroma, histological preparations were prepared to clarify the diagnosis and study histomorphological changes in the tissues. Atheroma of the skin in dogs was most often registered in old animals, which were more than 9 years old at the time of diagnosis. At the same time, such pathology was most often localized in dogs in the area of the head and neck. Among the breeds, the Boxer turned out to be the most susceptible to the formation of sebaceous gland cysts. Also, the incidence among females was 75% of all cases of registered diseases. Histological studies revealed the prevalence of cases with the formation of multiple cysts – 67%, when a number of smaller formations are found near one huge atheroma, while cases of purulent inflammation were only 16%. Surgical removal of the atheroma was an effective method of treatment, while no cases of re-development of cysts were observed during the long postoperative follow-up. The obtained results make it possible to expand knowledge on the clinical manifestation, diagnosis and treatment of non-neoplastic skin diseases in domestic animals