Affiliation:
1. Research and Production Center “Pharmaceutical Protection”, Federal Medical Biological Agency
Abstract
The article on the basis of an analysis of the literature discusses promising areas for the development of antidote prophylaxis and treatment of acute cyanide poisoning. The chemical compounds mediating anticyanide activity by stimulating the main detoxification mechanisms of endogenous cyanide: sulfangen, cobinamide, α-ketoglutaric acid claimed to be potential cyanide antidotes, effective and safe for intramuscular and intraosseous injections, inhalation and oral administration.
Publisher
Russian Register of Potentially Hazardous Chemical and Biological Substances