INFLUENCE OF SODIUM THIOPENTAL ON CONSERVATION OF CONDITIONAL REFLEX OF PASSIVE AVOIDANCE IN RATS WITH DIFFERENT NERRVOUS SYSTEM EXCITABILITY-Reference-Cited by-同舟云学术

INFLUENCE OF SODIUM THIOPENTAL ON CONSERVATION OF CONDITIONAL REFLEX OF PASSIVE AVOIDANCE IN RATS WITH DIFFERENT NERRVOUS SYSTEM EXCITABILITY

Published:2018-02-28 Issue:1 Volume: Page:8-11
ISSN:0869-7922
Container-title:Toxicological Review
language:
Short-container-title:Toksikologičeskij vestnik

Author:

Shvetsov A. V.¹,Vaido A. I.²,Dyuzhikova N. A.²,Belskaya A. V.¹,Mikhailova M. V.¹,Skomorokhova E. B.³,Batotsyrenova E. G.¹

Affiliation:

1. Institute of Toxicology. Federal Medical and Biological Agency

2. I.P.Pavlov Institute of Physiology, Russian Academy of Sciences

3. Institute of Toxicology. Federal Medical and Biological Agency;I.P.Pavlov Institute of Physiology, Russian Academy of Sciences

Abstract

A study of the dynamics of preservation of the conditioned reflex of passive avoidance (passive avoidance response) in rats of two lines with different level of excitability of the nervous system was performed: with a high and low thresholds of excitability as normal and after exposure to sodium thiopental semi-lethal dose. It was shown that a long preservation of the memorable trace under standard conditions and a higher sensitivity to the sodium thiopental action manifest in rats with a high excitability threshold in comparison with low-excitable line of rats.

Publisher

Russian Register of Potentially Hazardous Chemical and Biological Substances

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