CLINICAL TOXICOLOGY AND FORENSIC ASPECTS OF THE EVALUATION OF THE TOXIC EFFECT OF ETHANOL IN CHILDREN

Author:

Klevno V. A.1,Ostapenko Yu. N.2,Maksimov A. V.1

Affiliation:

1. Bureau of Forensic Medical Expertise of the Moscow Region; M.F.Vladimirsky Moscow Regional Research Clinical Institute

2. Research and Applied Toxicology Center of the Federal Medical and Biological Agency; N.V. Sklifosovsky Research Institute for Emergency Medicine, Healthcare Department of Moscow

Abstract

The article presents the analysis of domestic and foreign literature on toxic effects of ethanol in children, statistics and the results of forensic investigations of children with the presence of ethanol in blood, forensic chemical and chemical toxicological studies of biological fluids taken from children and adolescents aged from 0 to 17 years and examined in the Bureau of Forensic Medical Expertise of the Moscow Region in 2003 – 2017, as well as clinical and statistical analysis of cases of ethanol poisoning in adolescents hospitalized in the toxicological department of intensive care of Moscow City Clinical Hospital № 5 in 2012 – 2015.

Publisher

Russian Register of Potentially Hazardous Chemical and Biological Substances

Reference13 articles.

1. Toxic effect of alcohol / Federal clinical recommendations of Interregional charitable public organization «Association of clinical toxicologists» ed. Ostapenko Yu.N. - Moscow, 20 - 50 p.(in Russian).

2. Nuzhnii V.P. Mechanisms and clinical manifestations of the toxic effect of alcohol: guide to addiction / ed. Ivanez N.N. M.: Medical Practice, 20 Vol. 1: 74-94 (in Russian).

3. Luzhnikov E.A., Sukhodolova G.N. Acute poisoning in adults and children. Eksmo Ltd., 20- 560 p. (in Russian).

4. 2010 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 28th Annual Report. Bronstein A.C., Spyker D.A., Cantilena L.R. Jr, Green J.L., Rumack B.H., Dart R.C. Clin Toxicol (Phila). 2011; Dec; 49(10):910 - doi: 10.3109/15563650.2015.1102927.

5. HYPERLINK «http://www.uptodate.com.ololo.sci-hub.io/contents/ethanol-intoxication-inchildren-epidemiology-estimation-of-toxicity-andtoxic-effects/abstract/2» Vogel C., Caraccio T., Mofenson H., Hart S. Alcohol intoxication in young children. J Toxicol Clin Toxicol 1995; 33: pmid: 7837310.

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