Upregulation of energy metabolism-related, p53-target TIGAR and SCO2 in HuH-7 cells with p53 mutation by geranylgeranoic acid treatment
Author:
Affiliation:
1. Molecular and Cellular Biology, Graduate School of Human Health Science, University of Nagasaki
Publisher
Biomedical Research Press
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Link
https://www.jstage.jst.go.jp/article/biomedres/36/6/36_371/_pdf
Reference30 articles.
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2. 2 Bensaad K, Cheung EC and Vousden KH (2009) Modulation of intracellular ros levels by tigar controls autophagy. EMBO J 28, 3015–3026.
3. 3 Bensaad K, Tsuruta A, Selak MA, Vidal MN, Nakano K, Bartrons R, Gottlieb E and Vousden KH (2006) Tigar, a p53-inducible regulator of glycolysis and apoptosis. Cell 126, 107–120.
4. 4 Dai Q, Yin Y, Liu W, Wei L, Zhou Y, Li Z, You Q, Lu N and Guo Q (2013) Two p53-related metabolic regulators, tigar and sco2, contribute to oroxylin a-mediated glucose metabolism in human hepatoma hepg2 cells. Int J Biochem Cell Biol 45, 1468–1478.
5. 5 Green DR and Chipuk JE (2006) P53 and metabolism: Inside the tigar. Cell 126, 30–32.
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