Formulation Development and Evaluation of a Polyherbal Suspension Containing <i>Curcuma longa</i>, <i>Ocimum sanctum</i> and <i>Azadirachta indica</i> with Improved Antimicrobial Activity

Abstract

A lack of global political will to mobilise resource to fight tuberculosis is major challenge in ending tuberculosis. The polyherbal formulations are best alternative, as they are economic, environmentally friendly and easily available than modern drugs. In present study, a polyherbal suspension with extracts of C. longa, A. indica and O. sanctum was developed and characterized. The developed suspension was found satisfactory with respect to odour, colour, taste, pourability, pH, viscosity, zero microbial count, particle size, percentage ease of disposability, aesthetic characteristic, sedimentation, zeta potential and does not show the crystal growth, polyherbal formulation exhibited significantly inhibited the growth of H37Rv and MIC is also comparable to those of standard agents.