Author:
Archna Singh ,Avijit Mazumder ,Saumya Das ,Anmol Kanda
Abstract
Liver ailments are significant contributors to human illness and death globally. The prevalence of liver disorders is increasing owing to the widespread prevalence of hepatitis and alcohol addiction. These conditions can be triggered by infection, trauma, exposure to pharmaceuticals or hazardous substances, autoimmune disorders, or genetic abnormalities resulting in the accumulation of harmful substances. Despite advances in understanding the causes underlying hepatic dysfunction, no standard pharmaceutical therapy is available. The only currently advised option is to make lifestyle changes such as diet, intermittent fasting, and increased physical exercise. However, a lack of compliance continues to impede this strategy. As a result, there is an apparent need to characterize novel therapeutic alternatives. Current advances in the communication between the gut and hepatic tissue open new avenues for better explaining the molecular mechanisms behind the pathology of hepatic illness. Natural bioactive compound research has emerged as an appealing strategy for overcoming lifestyle change resistance. The current study aims to review some of the identified compounds and other herbal approaches with favourable characteristics to hepatic health. This review study discusses their protective properties, mode of action in ameliorating the major pathological events involved in liver disorders, and therapeutic applications.
Publisher
Informatics Publishing Limited