A Review on Phytoconstituents and Metal Complexes for the Treatment of Tuberculosis

Author:

Sk Zakki Uddin ,Nirupama Panda ,Anjana G. V.,Kathiravan M. K.

Abstract

Tuberculosis (TB) is an infectious lung disease. Tiny droplets discharged into the air during cough and sneezes by an individual can transmit the bacteria that cause tuberculosis from one person to another. More than one million people die each year as a result of the communicable disease tuberculosis. Anti-TB allopathic drugs have been administered to treat the disease’s symptoms; however, they can produce negative side effects such as hepatitis, hypersensitivity reactions, nausea, vomiting, etc. As a result of the toxicity and side effects of allopathic medicines, the use of herbal medicine is growing in popularity. Since ancient times, medicinal plants have been used to treat illnesses. Alkaloids, coumarins, flavonoids, polyphenols, terpenoids, quinines, and other secondary metabolites that have antibacterial activity are produced by plants and may be helpful in the treatment of tuberculosis. This review aims to explore the possible uses of medicinal herbs and metal complexes with antitubercular capabilities.

Publisher

Informatics Publishing Limited

Subject

Pharmacology

Reference46 articles.

1. Sudre P, Ten Dam G, Kochi A. Tuberculosis: A global overview of the situation today. Bulletin of the World Health Organization. 1992; 70(2):149.

2. Joseph J, Nagashri K, Janaki GB. Novel metal based antituberculosis agent: Synthesis, characterization, catalytic and pharmacological activities of copper complexes. European Journal of Medicinal Chemistry. 2012; 49:151-63. https://doi.org/10.1016/j.ejmech.2012.01.006

3. Rafique S, Idrees M, Nasim A, Akbar H, Athar A. Transition metal complexes as potential therapeutic agents. Biotechnology and Molecular Biology Reviews. 2010; 5(2):38-45.

4. Rai M, Ingle AP, Birla S, Yadav A, Santos CA. Strategic role of selected noble metal nanoparticles in medicine. Critical Reviews in Microbiology. 2016; 42(5):696-719.

5. Keri RS, Sasidhar BS, Nagaraja BM, Santos MA. Recent progress in the drug development of coumarin derivatives as potent antituberculosis agents. European Journal of Medicinal Chemistry. 2015; 100:257-69. https://doi.org/10.1016/j.ejmech.2015.06.017

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