The Effect of <i>Sira Vedha</i> (Phlebotomy) at Right Elbow Joint in the Management of Non-alcoholic Fatty Liver Disease - Randomized Controlled Clinical Trial

Abstract

Introduction: Sushruta stated that Sira Vedha (phlebotomy) at Right Elbow Joint was used as a cure for Liver Diseases. Modern science is likewise on the same page as phlebotomy treatment for some liver illnesses, although the specific location for phlebotomy has not been specified. Similarly, there is diversity in the amount of blood extracted and the time length, with each research study recommending a different amount to be removed and the gap between two sessions. Both of the previously listed things are mentioned in the context of Ayurveda. Nonetheless, due to a lack of clinical proof, it cannot be practiced reliably in normal exercise. As a result, clinical proof for liver illnesses is required to confirm Sushruta’s theory. Methodology: 111 eligible patients with Non-Alcoholic Fatty Liver Disease (NAFLD) Grade I/II were randomly assigned to the control (group A) or trial (group B) groups in the pilot research (group B). After obtaining written informed permission, blood samples from each patient were collected for LFT and lipid profile testing. The patients in Group A were then just counseled to make dietary changes. Group B patients underwent dietary changes as well as Sira Vedha (phlebotomy) with 65 cc blood three times in 15 days. Checked hemoglobin before each phlebotomy for safety considerations before discontinuing the patient. The blood sample was taken before enrollment in the study and after the final follow-up, which was on the 60th day. Results: The serum results from the first and last follow-ups were compared. This study found that group B considerably improved in liver enzymes and lipid profile (P<0.050) when compared to group A. As a result, we may infer that phlebotomy can enhance liver enzymes and lipid profiles in NAFLD patients.