Profiling of Immunomodulatory Flavonois From Leafy Vegetables Available in West Bengal - An Overview of Their Mechanism of Action

Abstract

In recent years, the increasing incidence of autoimmune diseases such as cancer and viral diseases including COVID-19 poses a serious problem in terms of prevention, diagnosis, prognosis and therapy. Various kinds of active immunomodulatory ingredients are one of the main components of the continuous breakthroughs of pharmaceuticals until recent research. Flavonoids are significant phytochemicals that are thought to be principally responsible for plants’ immunomodulation function. These phytochemicals can also serve as a model for the creation of safe and effective immunomodulators as potential treatments for the prevention and treatment of various immune-related disorders. Leafy vegetables give stronger support for human health due to their overlapping nutritional and therapeutic advantages. The goal of the present review was to profile the immunomodulatory flavonoids from the leafy vegetables of West Bengal to support the prevalent immune-related disorders worldwide. The majority of the leafy vegetables with significant immunomodulatory action are outlined, along with their potential mechanisms and quantity of the response flavonoids. The present work will pick the interest of researchers and promote additional studies on these leafy vegetables-based immunomodulation agents as prospective therapies for the treatment the various immune-suppressed disorders in future days.