Author:
Koshire Alka Rajesh,Godse Amala Anirudha,Phulkar Sarita,Pawar Hemant
Abstract
Aims: To compare hemodynamic changes occurring due to Propofol and Etomidate during general anesthesia as induction agents at a Tertiary Care Centre. Materials and Methods: 68 Adult ASA1 and ASA 2 Patients undergoing elective surgeries under gender anaesthesia in the department of Anaesthesia, Medical college and tertiary health care Centre after considering and satisfying the inclusion and exclusion criteria were selected and divided in two equal groups. They were given Propofol (2mg/kg) and Etomidate (0.3mg/kg) and hemodynamics were compared. Results: Etomidate was having more stable hemodynamic conditions as compared to Propofol induced anaesthesia. There was significant reduction in heart rate and blood pressure leading to hypotension in propofol group while etomidate group had stable hemodynamics. Conclusion: This study concludes that etomidate is a better agent for induction than propofol in view of hemodynamic stability.
Publisher
Informatics Publishing Limited
Reference17 articles.
1. Stone JG, Foex P, Sear JW, Johnson LL, Khambatta HJ, Triner L. Risk of myocardial ischaemia during anaesthesia in treated and untreated hypertensive patients. British Journal of Anaesthesia. 1988; 61:675–9. https://doi.org/10.1093/bja/61.6.675. PMid:3207540
2. Riznyk L, Fijalkowska M, Przesmycki K. Effects of thiopental and propofol on heart rate variability during fentanyl-based induction of general anesthesia. Pharmacological Reports. 2005; 57:128–34.
3. Basu S, Mutschler DK, Larsson AO, Kiiski R, Nordgren A, Eriksson MB. Propofol (Diprivan-EDTA) counteracts oxidative injury and deterioration of the arterial oxygen tension during experimental septic shock. Resuscitation. 2001; 50:341–8. https://doi.org/10.1016/S0300-9572(01)00351-3
4. Kelicen P, Ismailoglu UB, Erdemli O, Sahin-Erdemli I. The effect of propofol and thiopentone on impairment by reactive oxygen species of endothelium-dependent relaxation in rat aortic rings. European Journal of Anaesthesiology. 1997; 14:310–5. https://doi.org/10.1046/j.1365-2346.1997.00110.x. PMid:9202920
5. Hiller SC, Mazurek MS. Monitored anesthesia care. In: Barash PG, Cullen BF, Stoelting RK, editors. Clinical Anesthesia. 5th ed. Philadelphia: Lippincott Williams and Wilkins; 2006. p. 1246–61.
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