Evaluation of Outcome In Patients Suffering from COVID-19 Infection – A Retrospective Study

Abstract

Background: Severe Acute Respiratory syndrome Coronavirus–2 (SARS –Cov-2) named COVID-19 (Coronavirus Disease – 2019) pandemic is the biggest public health problem the human mankind is facing today. Objective: Primary objective was to determine in-hospital mortality within 30 days of admission. The secondary objective was to analyze the risk factors leading to deterioration and poor outcome in patients suffering from COVID-19 infections. Material and Methods: This Multicentric, Retrospective Observational cohort study was conducted in confirmed COVID-19 infected patients admitted in three COVID care centers of Jalandhar city during January 2020 to June 2021. The data of admitted Patients was retrospectively analyzed. The study has been approved by Institutional Ethics Committee of Punjab Institute of Medical Sciences, Jalandhar reference number PIMS/IEC/22/10. Results: Total 1139 patients were admitted in three COVID centers of the city during the period of January 2020 to June 2021. The mean age of the patients was 54.96 ±15.43, 706 (62%) were male and 433 (38%) were female, 523 (45.9%) belong to rural area and 616 (54.1%) belong to urban area. 580 (50.9%) have comorbid condition while 559 (49.1%) do not have any comorbidity. The total number of deaths reported was 225 (19.8%). Comorbidities were seen in 580 patients (50.9%) with 126 deaths (21.7%). Out of 1139, 336(29.5%), 211(18.5%), 31(2.7%), 2(0.2%) had one, two, three and four number of comorbidities respectively. The maximum number of deaths i.e. 140 deaths (12.3%) were seen in the age group of 51–75. Conclusion: Maximum mortality rate was seen in the age group of 50-75 years of age, with significant number of deaths in rural population with two comorbidities in patients suffering from Diabetes and hypertension.