Therapeutic efficacy of Enroflon gel in the treatment of clinical and subclinical mastitis in cattle

Abstract

Relevance. The work is devoted to the study of the therapeutic effect of the drug Enroflon gel on cows of the Holstein black-and-white breed during the period of intensive lactation. Due to the fact that drugs for intracisternal administration based on enrofloxacin and ketoprofen were not used at domestic livestock enterprises, the goal was to study the therapeutic efficacy of the drug in the treatment of clinical and subclinical mastitis of bacterial etiology.Methods. The production experience was carried out in the conditions of the economy of LLC “Babaevo”, with. Babaevo, Sobinsky District, Vladimir Region. Two experimental groups of Holsteinized black-and-white cows with live weight of 500–600 kg with a milk yield of 6000–7000 l/year were formed. When determining the number of somatic cells in milk samples, we used the Kenotest system and the Somatos-V-2K milk analyzer. The presence of a residual amount of antibiotic in milk was determined by inhibitory microbiological tests. Hematological parameters in cows were carried out at the Department of Disease Diagnostics, Therapy, Obstetrics and Animal Reproduction of the Moscow State Academy of Medical Sciences K.I. Scriabin. The drug Enroflon gel was injected intracisternally into the inflamed udder lobe in clinical and subclinical mastitis in cows during lactation. For 15 days, the clinical condition of the cows was monitored. The investigated drug was manufactured at LLC “VIC-Animal Health”.Results. In the treatment of clinical and subclinical mastitis of bacterial etiology in cows during the period of intensive milk production with the use of Enroflon gel, a high therapeutic effect was obtained: 80 and 100%, respectively. The clinical condition of cows during production experiments without deviations from the physiological norm.