Abstract
Flavocillin, a newly discovered beta-lactam antibiotic, shows promise in its ability to be a TrxR inhibitor. Through our docking experiments, we identified key residues in the docking process, namely ALA295, GLN294, GLY41, GLY12, GLY36, GLY38, SER13, PRO15, ALA16, SER298 that prove the idea that this molecule can increase the susceptibility of various bacteria to beta-lactams, combined with this TrxR inhibitor. Moreover, HIV is known to thrive with the help of reduced oxidative stress. The opposite effect could minimize the viral copies, without the intervention of antiviral drugs.