Abstract
The literature review provides up-to-date data on the main causes of acute renal injury in patients with COVID-19 with complications of hypoxia, respiratory failure and sepsis against the background of various types of drug treatment. The relationship of renal insufficiency with the effect of the use of diuretics and nonsteroidal anti-inflammatory drugs is analyzed. The assessment of the combined use of angiotensin converting enzyme inhibitors and angiotensin-II receptor blockers and their possible role in the pathogenesis of acute renal injury is given.The nephroprotective effect of antiviral drugs, steroid hormones and azithromycin is evaluated.