Abstract
Since the discovery of the new coronavirus in December 2019, a pandemic has set in, impacting quality of life not only by vulnerability to the course of infection, but also in its lingering consequences after the viral picture, popularly known as long covid. Although the mechanism and all the factors involving long covid are still uncertain, many diseases have been greatly mentioned, being obstructive sleep apnea one of them, due to its strong correlation with obesity and the greater potential for pro-inflammatory signaling through deregulation of the sirtuin pathway. In this present study, we sought to evaluate the possible beneficial impact of physical activity as a remodeling factor of inflammatory signaling through the activation of the SIRT-1 pathway.