TRANSPLACENTAL TRANSMISSION OF TUBERCULOSIS INFECTION IN COWS INFECTED WITH MYCOBACTERIUM BOVIS-Reference-Cited by-同舟云学术

TRANSPLACENTAL TRANSMISSION OF TUBERCULOSIS INFECTION IN COWS INFECTED WITH MYCOBACTERIUM BOVIS

Published:2021-12-14 Issue:2 Volume: Page:18-25
ISSN:2224-168X
Container-title:Epizootology Immunobiology Pharmacology Sanitation
language:
Short-container-title:Èpizootol. immunobiol. farmakol. sanit.

Author:

Lysenko A. P.,Kuchvalsky M. V.,Vysotsky A. E.,Pritychenko A. N.,Krasnikova E. L.,Yakobson E. I.

Abstract

A culture of M. bovis was isolated from liver and spleen homogenate, from tissues and amniotic fluid of 8- and 6-month-old fetuses of cows with local tuberculous changes in the lymph nodes of the lungs. It serves as confirmation of the transplacental infection transmission. The transfer occurred due to filtering virus-like forms of tuberculosis myco-bacteria, which were transformed into non-acid-fast, partially acid-fast and typical forms of tuberculosis mycobacteria in tissues, which can lead to the emergence of endogenous tuberculosis after birth or create an invisible reservoir of infection, because non-acid-fast forms of mycobacterium do not induce the development of hypersensitivity to tubercu-lin. In addition, the persistence of modified and typical mycobacteria in fetuses can lead to immunological tolerance to their antigens. The results obtained confirm the correctness of the regulations on the isolated rearing of calves born in disad-vantaged conditions, followed by fattening and delivery for slaughter.

Publisher

National Academy of Sciences of Belarus

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