DETECTION OF MARKERS OF LATENT TUBERCULOSIS INFECTION IN ULTRAPASTEURIZED MILK PRODUCED IN DIFFERENT COUNTRIES-Reference-Cited by-同舟云学术

DETECTION OF MARKERS OF LATENT TUBERCULOSIS INFECTION IN ULTRAPASTEURIZED MILK PRODUCED IN DIFFERENT COUNTRIES

Published:2021-12-11 Issue:2 Volume: Page:13-25
ISSN:2224-1647
Container-title:Ecology and Animal World
language:
Short-container-title:Èkol. životn. mir

Author:

Lysenko A. P.,Kuchvalskiy M. V.,Yakobson E. I.,Krasnikova E. L.,Pritychenko A. N.

Abstract

The genome of tuberculosis mycobacterium (MTB) was detected in ultrapasteurized milk from countries that have and do not have free status from bovine tuberculosis. Also cell wall deficient (CWD) MTB were isolated from all milk samples, that indicates latent tuberculosis infection in herds supplying milk to dairy enterprises. It was found that ultrasmall (less than 0.22 μm) thermally stable protective forms of MTB were present in milk. They can restore viability as CWD MBT and possibly play a role in the induction of oncogenesis and other pathological conditions. The existing criteria determining the status of herds do not allow the detection of latent tuberculosis infection, since persistent CWD (L-) forms of MBT do not cause the development of macroscopic changes and hypersensitivity to tuberculin. To identify the real situation in the herds, it is necessary to use PCR and to inoculate special nutrient media with blood and milk mixed with mycobacterial growth stimulants.

Publisher

National Academy of Sciences of Belarus

Reference29 articles.

1. Юсковец, М. К. Туберкулез сельскохозяйственных животных и птиц / М. К. Юсковец. – Минск : Государственное издательство сельскохозяйственной литературы БССР, 1962. – 447 с.

2. Olmstead, A. L. An Impossible Undertaking: The Eradication of Bovine Tuberculosis in the United States / A. L. Olmstead, P. W. Rhode // The Journal of Economic History. – 2004. – Vol. 64. – № 3. – P. 734–772.

3. Palmer, M. V. Bovine Tuberculosis and the Establishment of an Eradication Program in the United States: Role of Veterinarians / M .V. Palmer, W. R. Waters // Veterinary Medicine International. – 2011. – Vol. 2011. – P. 1–12.

4. Diagnosis of mycobacteria in bovine milk: an overview / C. A. D. Bolaños [et al.] // Revista do Instituto de Medicina Tropical de São Paulo. – 2017. – Vol. 59. – P. 1–13.

5. Nontuberculous mycobacteria in milk from positive cows in the intradermal comparative cervi-cal tuberculin test: implications for human tuberculosis infections / C. A. D. Bolaños [et al.] // Revista do Instituto de Medicina Tropical de São Paulo. – 2018. – Vol. 60. – P. 6.