Reduced numbers of peripheral blood CD27+ IgD– memory B cells in patients with aggressive periodontitis

Author:

Jentsch Holger,Purschwitz Regina,Stingu Catalina Suzana,Schmidt Jana,Sack Ulrich

Abstract

AbstractAggressive periodontitis (AgP) is a multifactorial disease with unknown association to the development and function of peripheral lymphocytes. The aim of this study was to elucidate a connection between the periodontal condition in 10 patients with AgP and their potential state of immunodeficiency. Based on full periodontal examination and radiographs, 10 females (ages 29.8±8.62 years) with established diagnosis of aggressive periodontitis were included in this study. Flow cytometric analysis revealed substantial reduction of switched memory B cells (IgM

Publisher

Walter de Gruyter GmbH

Subject

Biochemistry (medical),Medical Laboratory Technology,Clinical Biochemistry

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